Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Blood Flow01:29

Blood Flow

Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Laminar and Turbulent Flow01:07

Laminar and Turbulent Flow

Fluid dynamics is the study of fluids in motion. Velocity vectors are often used to illustrate fluid motion in applications like meteorology. For example, wind—the fluid motion of air in the atmosphere—can be represented by vectors indicating the speed and direction of the wind at any given point on a map. Another method for representing fluid motion is a streamline. A streamline represents the path of a small volume of fluid as it flows. When the flow pattern changes with time, the streamlines...
Newtonian Fluid: Problem Solving01:18

Newtonian Fluid: Problem Solving

Newtonian fluids exhibit a constant viscosity, meaning their shear stress and shear strain rate are directly proportional. This property ensures a predictable and stable response to applied forces, maintaining a linear relationship between force and flow. Examples include water, air, and light oils, consistently demonstrating this proportional behavior regardless of external conditions.
A velocity gradient forms within the fluid when a Newtonian fluid is placed between two parallel plates, with...
Euler's Equations of Motion01:28

Euler's Equations of Motion

In fluid mechanics, shear stresses arise from viscosity, which represents a fluid's internal resistance to deformation. For low-viscosity fluids, like water, these stresses are minimal, simplifying flow analysis by allowing the fluid to be treated as inviscid, or frictionless. In an inviscid fluid, shear stresses are absent, leaving only normal stresses, which act perpendicularly to fluid elements. Notably, pressure — defined as the negative of the normal stress — remains uniform across...
Navier–Stokes Equations01:28

Navier–Stokes Equations

For incompressible Newtonian fluids, where density remains constant, stresses show a linear relationship with the deformation rate, defined by normal and shear stresses. Normal stresses depend on the pressure exerted on the fluid and the rate of deformation in specific directions, which determines how fluid flows under varying pressures. Shear stresses, on the other hand, act tangentially across fluid layers. They explain how adjacent fluid layers slide relative to one another, connecting...
Applications of Integration to Find Blood Flow01:27

Applications of Integration to Find Blood Flow

Blood flow through a cylindrical blood vessel can be mathematically described using the principles of laminar flow, a regime in which fluid moves smoothly in parallel layers. In this model, the velocity of the blood is not uniform across the cross-section of the vessel; rather, it varies with the radial distance from the center. The maximum velocity occurs along the central axis, decreasing progressively toward the vessel walls, where it reaches zero due to viscous drag.Approximating Blood...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Lower body negative pressure identifies altered central vein characteristics without accompanying changes to baroreflexes in astronauts within hours of landing.

Scientific reports·2024
Same author

The effects of slow breathing on postural muscles during standing perturbations in young adults.

Experimental brain research·2022
Same author

Osteoarthritis, cerebrovascular dysfunction and the common denominator of inflammation: a narrative review.

Osteoarthritis and cartilage·2018
Same author

Impaired Cerebrovascular Function in Coronary Artery Disease Patients and Recovery Following Cardiac Rehabilitation.

Frontiers in aging neuroscience·2016
Same author

Neural Control of Vascular Function in Skeletal Muscle.

Comprehensive Physiology·2016
Same author

Climate change. What role for short-lived climate pollutants in mitigation policy?

Science (New York, N.Y.)·2013

関連する実験動画

Updated: Jul 7, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
07:30

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

Published on: November 3, 2015

心不全における血流の動態

J K Shoemaker1, H L Naylor, C S Hogeman

  • 1Department of Medicine, Section of Cardiology, Pennsylvania State University College of Medicine, Hershey, PA, USA. kshoemak@gcrc.hmc.psghs.edu

Circulation
|June 15, 1999
PubMed
まとめ

心不全 (HF) の患者は,運動中に筋肉の糖解が増加することを示しています. 激しい運動中に前腕の血管伝導率の低下は,血管収縮の強化がHFの疲労に寄与することを示唆しています.

科学分野:

  • 心血管生理学 心血管の生理学
  • 骨格筋の代謝について
  • 心不全 病理生理学 心不全 病理生理学

背景:

  • 心不全 (HF) の運動不耐性は,血管拡張の障害,血管収縮の増加,および筋肉代謝の変化と関連しています.
  • これらの要因は,身体活動中にHF患者の経験する疲労に寄与します.

研究 の 目的:

  • 心不全 (HF) 患者のリズム的な前腕運動に対する血管および代謝反応を,健康な対照群と比較して調査する.
  • 運動中の酸素供給と吸収の時間経過に対するHFの影響を調べる.
  • HF患者の運動中の血管収縮,特にメタボレフレクスを評価する.

主な方法:

  • 9人のHF患者と9人の対照群 (CTL) に2つの運動プロトコルを使用した.
  • プロトコル1は,酸素の供給と吸収の動態を評価した.
  • プロトコル2では,メタボレフレクスを誘発するために,血性前腕運動中に血管収縮を評価した.

主要な成果:

  • HF患者は,同様の血流と酸素の吸収にもかかわらず,CTLと比較して,運動の4分後に静脈乳酸とH+レベルが高かった.
  • 低血圧運動に対する平均動脈圧の反応は,グループ間で比較可能であった.
  • HFの患者は,前腕の血流と血管伝導が,制御群とは異なり,環境運動と比較して,不全性運動中に減少したことを示した.
キーワード:
NASA 規律 心肺循環器系非NASAのセンターです.

さらに関連する動画

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

関連する実験動画

Last Updated: Jul 7, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
07:30

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling

Published on: November 3, 2015

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow
09:34

Pneumococcus Infection of Primary Human Endothelial Cells in Constant Flow

Published on: October 31, 2019

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
13:07

Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

Published on: January 15, 2022

結論:

  • HFにおける適度な運動に対する増加した糖分分解性代謝反応は,血管拡張力学のみではなく,内在的な骨格筋の違いに起因する.
  • 前腕の血管伝導を高血圧で激しい不全性運動中に増やすことのできないことは,血管収縮の強化が運動疲労に大きく寄与することを示唆しています.