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Updated: Jul 15, 2026

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme
08:36

Separation of Mouse Embryonic Facial Ectoderm and Mesenchyme

Published on: April 12, 2013

SIL遺伝子は,マウスの胚性軸向発達と左-右の仕様のために必要です

S Izraeli1, L A Lowe, V L Bertness

  • 1Genetics Department, Medicine Branch, National Cancer Institute, NIH, Bethesda, Maryland 20889-5105, USA.

Nature
|June 29, 1999
PubMed
まとめ

SIL遺伝子が欠けているマウスの胚は,ミッドラインの欠陥を示し,ソニック・ヘッジホッグ (Shh) 信号伝達を妨害し,ランダム化された心臓ループにつながります. これは,ミドルラインの破壊のタイミングと重度が,左から右のパターニングにどのように影響するかを強調しています.

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