c-Ablとp73alphaの相互作用と,アポトーシスを誘発する彼らの協力

R Agami1, G Blandino, M Oren

  • 1Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot, Israel.

Nature
|July 3, 1999
PubMed
まとめ

この研究では,腫瘍抑制剤p73alphaは,そのアポプトティック機能のためにキナーゼc-Ablを必要としていることが明らかになりました. DNA損傷は,このp73とc-Ablのプロアポプトシス信号伝達経路を活性化します.

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