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Updated: Jul 13, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

p73は,DNA損傷に対するアポプトティック反応においてチロシンキナーゼc-Ablによって調節される

Z M Yuan1, H Shioya, T Ishiko

  • 1Department of Cancer Cell Biology, Harvard School of Public Health, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA.

Nature
|July 3, 1999
PubMed
まとめ

タイロシンキナーゼc-Ablはp73タンパク質に結合し,リン酸化し,アポトーシスにおけるその役割を刺激する. この相互作用は,DNA損傷によって引き起こされる細胞死にとって極めて重要であり,p73.3のための新しい調節経路を強調しています.

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Knockdown of FAM83A to Verify Its Role in Cervical Cancer Cell Growth and Cisplatin Sensitivity04:20

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