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Updated: May 1, 2026

Expression, Purification, and Antimicrobial Activity of S100A12
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Expression, Purification, and Antimicrobial Activity of S100A12

Published on: May 13, 2017

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RAGEは新しい炎症促進軸を媒介する:S100/カルグラヌリンのポリペプチドのための中央細胞表面受容体

M A Hofmann1, S Drury, C Fu

  • 1College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

Cell
|July 10, 1999
PubMed
まとめ

AGE (RAGE) の受容体はEN-RAGEとS100タンパク質に結合し,炎症を引き起こす. この相互作用を遮断すると,動物モデルにおける炎症反応が低下し,慢性炎症疾患の治療のための新たな標的が明らかになる.

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