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Updated: Jul 20, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

DNA依存型タンパク質キナーゼは,DNA損傷に対するp53依存型反応には必要ありません

G S Jimenez1, F Bryntesson, M I Torres-Arzayus

  • 1Gene Expression Laboratory, The Salk Institute, La Jolla, California 92037, USA.

Nature
|July 14, 1999
PubMed
まとめ

DNA依存タンパク質キナーゼ (DNA-PK) は,DNA損傷後の腫瘍抑制剤p53の活性化には必要ありません. 研究によると,p53応答はDNA-PKが欠けている細胞で機能し続け,以前の仮定に異議を唱えている.

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