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Updated: Jul 10, 2026

Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Published on: July 4, 2016

GCN5ヒストンアセチルトランスフェラーゼの触媒ドメインの溶液構造は,コエンザイムAに結合する

Y Lin1, C M Fletcher, J Zhou

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|July 14, 1999
PubMed
まとめ

テトラヒメナGCN5 (tGCN5) は,遺伝子転写に不可欠なヒストンアセチルトランスフェラーゼです. その触媒ドメイン構造は,コエンザイムAがどのように結合し,tGCN5がヒストンH3ペプチドと相互作用して遺伝子発現を活性化することを明らかにします.

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