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"ホワイトコート"効果の間,筋肉と皮膚の交感神経のトラフィック
1Cattedra di Medicina Interna, Università di Milano, Ospedale S. Gerardo, Monza, and Centro di Fisiologia Clinica e Ipertensione, IRCCS, Milano, Italy.
Circulation
|July 21, 1999
まとめ
血圧測定中の"ホワイトコート"効果は,血圧と心拍数を増加させます. この反応には,筋肉の交感神経の活動が低下し,皮膚の交感神経の活動が増加します.
科学分野:
- 心血管生理学 心血管の生理学
- 自律神経系の研究
背景:
- スフィグモマノメトリックによる血圧測定は,警戒反応を引き起こし,血圧と心拍数を上昇させます.
- この"ホワイトコート"効果が交感神経の伝達に与える影響は,まだ未知のままです.
研究 の 目的:
- "ホワイトコート"効果の間に交感神経の流れの変化を調査する.
- 血圧測定によるストレスに対する筋肉と皮膚の交感神経の特定の反応を決定する.
主な方法:
- マイクロニューログラフィーは,10人の軽度の高血圧患者の筋肉と皮膚の交感神経の活動を測定するために使用されました.
- 動脈血圧と心拍数は,それぞれフィナプレスとECGを使用してモニタリングされました.
- 測定は,コントロール期間,血圧測定のための医師の診察,および回復期間中に行われました.
主要な成果:
- 医者の診察は,皮膚の交感神経の交通の有意な増加 (+38.6%) を引き起こしました.
- 対照的に,筋肉の交感性神経の動きは著しく減少した (-25.5%).
- これらの変化は訪問中に持続し,その後徐々に解決しました.
結論:
- 血圧測定に対する警報反応は,皮膚におけるシンパト刺激と筋肉におけるシンパト抑制という,異なる交感反応を誘発する.
- この異なるアドレネルギー神経系の行動が"白衣"現象を特徴づける.
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