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コンタクトレンズに関連した微生物性角膜炎の発生率とその関連疾患率
K H Cheng1, S L Leung, H W Hoekman
1Rotterdam Eye Hospital, The Netherlands.
Lancet (London, England)
|July 27, 1999
まとめ
微生物性角膜炎の発生率は,長時間着用ソフトコンタクトレンズで最も高い. コンタクトレンズの夜間着用は,目の感染症の重大なリスクがあるため,推奨すべきではありません.
科学分野:
- オフタルモロジック (眼科)
- エピデミオロジー エピデミオロジー
- 微生物学 微生物学とは
背景:
- コンタクトレンズに関連した微生物性角膜炎の発生率と罹患率は,コンタクトレンズを使用する一般人群では依然として不確実である.
- この研究は,これらの疫学的側面を調査することを目的とした.
研究 の 目的:
- 異なるタイプのコンタクトレンズ着用に関連した微生物性角膜炎の発生率を決定する.
- 微生物性角膜炎に関連した眼疾患を評価する.
- 危険因子を特定し,公衆衛生上の勧告を伝える.
主な方法:
- オランダで前向きな疫学研究が行われました.
- 眼科医は,3か月の間に新しい微生物性角膜炎の症例を特定するために調査されました.
- 毎年実施される全国的な調査では,1994年から1997年にかけてのコンタクトレンズ着用率を推定した.
主要な成果:
- 微生物性角膜炎の92例が確認されました.
- 発生率は1万ユーザーあたり1.1 (日用硬体・ガス通透性),3.5 (日用軟体),20.0 (延時耐用軟体) となっている.
- 延長着用ソフトレンズを使用する人の発生率は著しく高かった (p<0.00001). Pseudomonas keratitisは,より悪い視覚的結果をもたらしました.
結論:
- 延長着用ソフトレンズを使用した微生物性角膜炎の発生率は,以前の米国データと比較できます.
- 進歩にもかかわらず,コンタクトレンズ材料の改善は,発生を減少させていません.
- 夜間にコンタクトレンズを着用することを強く推奨します.
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