遺伝的非ポリポシス結腸直腸がんの遺伝子検査結果の解釈:臨床的予備性検査への影響

S Syngal1, E A Fox, C Li

  • 1Brigham and Women's Hospital, Department of Population Sciences, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Mass 02115, USA.

JAMA
|July 28, 1999
PubMed
まとめ

遺伝性非ポリポシス結腸直腸癌 (HNPCC) の遺伝検査は,家族25.7%で病原性変異を特定し,臨床管理を支援しました. しかし,決定的な解釈は多くの人々にとって依然として困難であり,継続的な監視を必要とします.

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