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Updated: Jul 8, 2026

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures
06:53

Parallel Measurement of Circadian Clock Gene Expression and Hormone Secretion in Human Primary Cell Cultures

Published on: November 11, 2016

mCRY1とmCRY2は,日中時計のフィードバックループの負の部分の不可欠な構成要素です

K Kume1, M J Zylka, S Sriram

  • 1Laboratory of Developmental Chronobiology, Pediatric Service, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA.

Cell
|July 31, 1999
PubMed
まとめ

マウス・クリプトクローム (mCRY) タンパク質であるmCry1とmCry2は,日中時計の重要な構成要素である. これらのタンパク質は,ネガティブなフィードバックループで作用するCLOCK:BMAL1転写複合体を阻害することによって,遺伝子発現を調節する.

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