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Updated: Jul 16, 2026

Recombinant Retroviral Production and Infection of B Cells
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Published on: February 18, 2011

B細胞発達の後期段階でのRAG発現が継続し,免疫接種後の再誘導は明らかではない

W Yu1, H Nagaoka, M Jankovic

  • 1Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10021, USA.

Nature
|August 24, 1999
PubMed
まとめ

B細胞と呼ばれる免疫細胞は,発達中に再結合活性化遺伝子 (RAG) を発現する. この研究では,RAGの発現は未成熟のB細胞に広く広がり,成熟するにつれて減少することが明らかになり,以前のモデルに挑戦しています.

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Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production08:22

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