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Updated: Jul 24, 2026

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

加齢の遺伝子発現プロファイルと,カロリー制限による加齢の遅延

C K Lee1, R G Klopp, R Weindruch

  • 1Environmental Toxicology Center, Institute on Aging, Department of Genetics, University of Wisconsin, Madison, WI 53706, USA.

Science (New York, N.Y.)
|August 28, 1999
PubMed
まとめ

マウスの骨格筋の老化は,ストレス反応と代謝遺伝子発現の減少を示している. カロリー制限は,これらの変化を逆転させ,タンパク質の回転を増加させ,損傷を軽減するために代謝をシフトすることにより,老化を遅らせることを示唆します.

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