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Updated: Jul 18, 2026

A High-content Assay for Monitoring AMPA Receptor Trafficking
10:34

A High-content Assay for Monitoring AMPA Receptor Trafficking

Published on: January 28, 2019

ポスタシナプスAMPA受容体のポリアミン依存的促進は,ペアパルス抑うつ症に対抗する

A Rozov1, N Burnashev

  • 1Max-Planck-Institut für medizinische Forschung, Abteilung Zellphysiologie/Molekulare Neurobiologie, Heidelberg, Germany.

Nature
|October 19, 1999
PubMed
まとめ

ポリアミンは,脳のアルファ-アミノ-3-ヒドロキシ-5-メチル-4-イソクサゾールプロピオネート受容体 (AMPAR) チャンネルをブロックする. このブロックの活動に依存した解消はシナプス電流を強化し,神経回路の短期的な可塑性に貢献します.

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