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Updated: Jul 19, 2026

Stable DNA Motifs, 1D and 2D Nanostructures Constructed from Small Circular DNA Molecules
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14-3-3シグマは,DNA損傷後のミトシカストラフを防ぐために必要である

T A Chan1, H Hermeking, C Lengauer

  • 1The Johns Hopkins Oncology Center, Program in Human Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

Nature
|October 19, 1999
PubMed
まとめ

14-3-3シグマタンパク質の無活性化により,がん細胞がDNA損傷後に細胞分裂を停止することを防ぐ. これは細胞死につながり,G2チェックポイントの維持に14-3-3シグマの役割を示唆する.

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