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家族性HDL欠乏症におけるABC1遺伝子の変異と,欠陥コレステロール流出の異常

M Marcil1, A Brooks-Wilson, S M Clee

  • 1Xenon Bioresearch Inc, NRC Innovation Centre, Vancouver, British Columbia, Canada.

Lancet (London, England)
|October 26, 1999
PubMed
まとめ

ATP結合カセット (ABC1) 遺伝子の変異は,細胞のコレステロール流出を損なうことで,家族性高密度リポタンパク質 (HDL) 欠乏を引き起こす. これは,ABC1調節が,HDLレベルを上昇させるための潜在的な戦略であることを強調しています.

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