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Updated: Jul 22, 2026

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
10:54

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR

Published on: February 23, 2016

X線 difrractionによって観察されたイソペニシリンN合成酵素の反応サイクル

N I Burzlaff1, P J Rutledge, I J Clifton

  • 1The Dyson Perrins Laboratory and the Oxford Centre for Molecular Sciences, University of Oxford, UK.

Nature
|October 28, 1999
PubMed
まとめ

イソペニシリンN合成酵素 (IPNS) は,2つの鉄二酸化酸素媒介のリング閉塞を通してペニシリン生物合成を触媒する. IPNS反応中間物質のX線結晶学により,この複雑な酵素プロセスに関する重要な構造的洞察が得られる.

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