関連する実験動画

Updated: Jul 27, 2026

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay
19:05

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

T細胞によって獲得されたペプチド-MHC複合体のTCR媒介的内部化

J F Huang1, Y Yang, H Sepulveda

  • 1R. W. Johnson Pharmaceutical Research Institute, 3210 Merryfield Row, San Diego, CA 92121, USA.

Science (New York, N.Y.)
|November 5, 1999
PubMed
まとめ

抗原呈現細胞はペプチドメジャーヒストコンパティビリティ複合体 (pMHCs) をT細胞に転送し,T細胞の兄弟殺しを誘発する. この過程は,高いウイルス負荷の間にT細胞の疲労を説明し,免疫反応を抑制する可能性があります.

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