セラフィールドの核再処理工場の男性放射線労働者の子孫の死産
L Parker1, M S Pearce, H O Dickinson
1Department of Child Health, University of Newcastle upon Tyne, UK. Louise.Parker@ncl.ac.uk
Lancet (London, England)
|October 30, 1999
まとめ
セラフィールドでの父による電離放射線被曝は,死産のリスクの増加と関連していました. 原子力労働者におけるこの発見は,動物研究と一致する,しかしより高いリスクの見積もりを持つ,潜在的な世代を超えた効果を示唆しています.
科学分野:
- 環境衛生 環境衛生 環境衛生
- 生殖性毒理学 生殖性毒理学
- 放射線流行病学について
背景:
- イオン化する放射線は,ヒトの世代を超えたデータが限られている既知の変異性物質です.
- セラフィールド原子力発電所の労働者は,高い職業的放射線被曝にさらされています.
- この研究は,セラフィールドの労働者の子供における父親の放射線被曝と死産リスクを調査しています.
研究 の 目的:
- 父による電離放射線被曝が死産のリスクの増加と関連しているかどうかを判断する.
- 父親の受精前の放射線量と死産のリスクとの関連を定量化するために.
主な方法:
- カンブリア州における248,097人の生児と3,715人の死産の出生登録データの分析 (1950年-89年).
- 130人の死産児と,セラフィールドの男性放射線労働者のパートナーに生まれた9,078人の生産児を特定した.
- 社会的階級,出生年,父の年齢,出生順に調整したロジスティック回帰分析.
主要な成果:
- 妊娠前の父親による放射線被曝と死産リスク (OR/100 mSv:1.24) の間に有意な正の関連性がある.
- 生まれつきの異常,特に神経管の欠陥を持つ死産児のリスク増加が観察されました.
- モデルによると,130人中0~31.9人の死産は,父親の放射線被曝によるものかもしれない.
結論:
- 死産のリスクの増加は,父親の職業放射線被曝と相関しており,動物モデルと一致しています.
- ヒトにおける観察されたリスクの推定値は,動物研究よりも高い.
- 統計分析により,モデルフィットが確認され,測定されていない混同要因の証拠はありません.
さらに関連する動画
関連する概念動画
Types of Radioactivity
The most common types of radioactivity are α decay, β decay, γ decay, neutron emission, and electron capture.
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:
Alpha (α) decay is the emission of an α particle from the nucleus. For example, polonium-210 undergoes α decay:
Nuclear Fission
Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large number of different...
Nuclear Power
Controlled nuclear fission reactions are used to generate electricity. Any nuclear reactor that produces power via the fission of uranium or plutonium by bombardment with neutrons has six components: nuclear fuel consisting of fissionable material, a nuclear moderator, a neutron source, control rods, reactor coolant, and a shield and containment system.
Nuclear Fuels
Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...
Nuclear Fuels
Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...
Nuclear Fusion
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
Nuclear Transmutation
Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed protons being...
Biological Effects of Radiation
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they produce ions...


