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Updated: Jul 1, 2026

Bimolecular Fluorescence Complementation
08:54

Bimolecular Fluorescence Complementation

Published on: April 15, 2011

サイクリンB1の蓄積は,アナフェーズ促進複合体のE2FとサイクリンA依存の再配置を必要とします

C Lukas1, C S Sørensen, E Kramer

  • 1Institute of Cancer Biology, Danish Cancer Society, Copenhagen.

Nature
|November 5, 1999
PubMed
まとめ

細胞循環の調節には,E2F/DP転写因子を制御する網膜芽細胞腫タンパク質 (pRb) 家族が関与しています. この研究では,サイクリンA/Cdk2によるE2F依存Cdh1のリン酸化が,タイムリーなサイクリンB1の蓄積と細胞周期の調整に不可欠であることを明らかにしています.

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