関連する実験動画

Updated: Jul 10, 2026

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
08:31

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

Published on: June 8, 2018

ATM依存型Brca1のリン酸化が,二重鎖の断裂に対するDNA損傷反応において要求される

D Cortez1, Y Wang, J Qin

  • 1Verna and Mars McLean Department of Biochemistry and Molecular Biology, Howard Hughes Medical Institute, Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|November 5, 1999
PubMed
まとめ

ATMキナーゼはDNA損傷後にBrca1タンパク質をリン酸化し,これは放射線に対する細胞の反応に不可欠である. このATM-Brca1の相互作用は,放射線過敏症を予防するために不可欠であり,乳がんにおけるATMの役割を説明する可能性がある.

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Visualization of DNA Repair Proteins Interaction by Immunofluorescence07:55

Visualization of DNA Repair Proteins Interaction by Immunofluorescence

Published on: June 26, 2020

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging06:44

Assessment of Global DNA Double-Strand End Resection using BrdU-DNA Labeling coupled with Cell Cycle Discrimination Imaging

Published on: April 28, 2021

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