胎盤の断裂と不良の生理周期の結果
C V Ananth1, G S Berkowitz, D A Savitz
1Department of Obstetrics, Gynecology and Reproductive Sciences, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick 08901-1977, USA. ananthcv@epi.umdnj.edu
JAMA
|November 30, 1999
まとめ
胎盤の断裂は,特に重度の分離では,死産のリスクを大幅に増加させます. 胎児の早産は,胎児の成長に影響を及ぼし,軽度の断絶でも一般的です.
科学分野:
- 産婦人科と産婦人科を担当しています.
- 産周医学は,産周医学である.
- 生殖器保健は,生殖器の健康についてです.
背景:
- 胎盤切断は,胎児間死亡,胎児のサイズ減少,妊娠期間短縮などの不良妊娠結果と関連しています.
- これらのアウトカムに対する胎盤分離の範囲の具体的な影響は不明である.
研究 の 目的:
- 胎盤剥離の寄与とその死産,早産,胎児の成長制限への影響を評価する.
- 胎盤分離の度合いによって伴うリスクを定量化するために.
主な方法:
- 1986年から1996年にかけての53,371人の妊娠を含む,遡及的なコホート研究.
- 死産,早産,胎児の成長制限に関するリスクと相対的なリスクを分析した.
- 胎盤分離の程度が有害な結果に与える影響を評価した.
主要な成果:
- 胎盤切断は,妊娠の1%で発生し,死産のリスク (aRR 8.9),早産リスク (aRR 3.9),胎児成長制限 (aRR 2.0) の増加と関連しています.
- 重度の胎盤分離 (≥50%) は,死産のリスクが著しく上昇した (75%の分離ではaRR 31.5).
- 軽度の胎盤分離 (25%) でさえも,早産のリスクが大幅に増加しました (aRR 5.5).
結論:
- 胎盤の断絶は死産,早産,胎児の成長制限に深刻に影響を与えます.
- 重度の胎盤分離は,死産のリスクを劇的に増加させます.
- 胎盤の分離がそれほど深刻でない場合でも,早産は一般的な合併症です.
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