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Updated: Jul 16, 2026

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis
09:16

Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis

Published on: December 14, 2015

結合組織成長因子遺伝子の過剰発現は,人間の大動脈の滑らかな筋肉細胞におけるアポトーシスを誘発する

K Hishikawa1, B S Oemar, F C Tanner

  • 1Cardiology, University Hospital Zürich, and Cardiovascular Research, Institute of Physiology, University Zürich, Switzerland, Department of Pharmacology, Teikyo University School of Medicine, Tokyo, Japan.

Circulation
|November 16, 1999
PubMed
まとめ

結合組織成長因子 (CTGF) は,血管の滑らかな筋肉細胞の増殖を抑制し,動脈硬化でアポトーシスを促進します. この発見は,心血管疾患における病変形成とプラークの安定性に関する新しい洞察を提供します.

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