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Van der Waals Interactions

Van der Waals Interactions

Atoms and molecules interact with each other through intermolecular forces. These electrostatic forces arise from attractive or repulsive interactions between particles with permanent, partial, or temporary charges. The intermolecular forces between neutral atoms and molecules are ion–dipole, dipole–dipole, and dispersion forces, collectively known as van der Waals forces.Polar molecules have a partial positive charge on one end and a partial negative charge on the other end of the molecule,...

Intermolecular Forces

Intermolecular Forces

Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen bonds, and dispersion...

Intermolecular Forces

Intermolecular Forces

Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen bonds, and dispersion...

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...

Noncovalent Attractions in Biomolecules

Noncovalent Attractions in Biomolecules

Noncovalent attractions are associations within and between molecules that influence the shape and structural stability of complexes. These interactions differ from covalent bonding in that they do not involve sharing of electrons.
Four types of noncovalent interactions are hydrogen bonds, van der Waals forces, ionic bonds, and hydrophobic interactions.
Hydrogen bonding results from the electrostatic attraction of a hydrogen atom covalently bonded to a strong-electronegative atom like oxygen,...

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関連する実験動画

Updated: Jul 13, 2026

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

縮小ゲルによる多点相互作用に基づく可逆分子吸収.

T Oya¹, T Enoki, A Y Grosberg

¹Department of Physics and Center for Materials Science and Engineering, Department of Chemistry, George R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. toyo@mit.edu

Science (New York, N.Y.)

|November 24, 1999

まとめ

研究者は,多点相互作用を使用して分子捕捉のためのポリマーゲルを開発しました. これらのスマートゲルは,結合力を逆向きに調整することができ,調節可能な分子認識能力を提供します.

さらに関連する動画

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

関連する実験動画

Last Updated: Jul 13, 2026

Spatial Separation of Molecular Conformers and Clusters

Spatial Separation of Molecular Conformers and Clusters

Published on: January 9, 2014

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly

Published on: February 6, 2020

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Covalent Attachment of Single Molecules for AFM-based Force Spectroscopy

Published on: March 16, 2020

科学分野:

ポリマー化学のポリマー化学について
材料科学材料科学とは
分子認識による分子認識

背景:

選択的分子捕獲のための材料の開発は,さまざまなアプリケーションにとって非常に重要です.
既存の方法には,調節可能な親和性や効率的なキャプチャメカニズムが欠けていることが多い.

研究の目的:

ターゲット分子に対する調整可能な親和性を持つポリマーゲルの設計のための一般的なアプローチを作成する.
ポリマーゲルと標的分子の間の反転可能な多点相互作用を可能にします.

主な方法:

ポリマーゲルを合成し,逆転可能な腫れと縮小のための特定のモノマーを組み込む.
標的分子の多点吸附センターとして設計されたマイノリティモノマーを組み込む.
affinity と monomer 濃度に関するパワー法則の分析を通じて,多点相互作用を実験的に検証する.

主要な成果:

多点相互作用を通じて標的分子を認識し,捕捉できるポリマーゲルの作成を実証した.
標的分子の親和性において,1次元の大きさを超える可逆的な変化を達成した.
観測された力法関係を通して,複数の点の相互作用が確認された.

結論:

提示されたアプローチは,調節可能な分子認識特性を持つスマートポリマーゲルの設計のための汎用性のあるプラットフォームを提供します.
これらのゲルは,標的分子の選択的および可逆的な捕獲を必要とするアプリケーションの潜在性を示しています.
この発見は,刺激反応性ポリマーネットワークにおける構造-性質関係に関する基本的な理解を提供します.