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Updated: Jan 30, 2026

Measuring Protein Binding to F-actin by Co-sedimentation
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PDZドメインに含まれるアクチン結合タンパク質であるShroomは,マウスにおける神経管形態変異のために必要である

J D Hildebrand1, P Soriano

  • 1Program in Developmental Biology and Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.

Cell
|December 10, 1999
PubMed
まとめ

マウスの新しい遺伝子変異,指定されたshroom (shrm) は,神経管の閉塞を妨害し,生まれつきの欠陥につながります. Shrmタンパク質は,胚の発達中の細胞構造と細胞骨格の調節に不可欠です.

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