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Updated: Jul 19, 2026

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain
10:08

Purification and Aggregation of the Amyloid Precursor Protein Intracellular Domain

Published on: August 28, 2012

人間の脳からアミロイド前駆体タンパク質ベータ・セクレタゼの浄化とクローン化

S Sinha1, J P Anderson, R Barbour

  • 1Elan Pharmaceuticals, South San Francisco, California 94080, USA. ssinha@elanpharama.com

Nature
|December 11, 1999
PubMed
まとめ

研究者らは,ヒトの脳内のアミロイド前駆タンパク質 (APP) のベータ分泌酵素分裂に起因する主要な酵素を特定した. この発見は,アルツハイマー病 (AD) の病原性および潜在的な治療標的の理解を前進させる.

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