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Updated: Jun 26, 2026

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メチレンテトラヒドロフォラート還元酵素のゲノタイプと早期発症冠動脈疾患

A Mager1, S Lalezari, T Shohat

  • 1Department of Cardiology, Rabin Medical Center, Beilinson Campus, Petah-Tiqva, and The Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Circulation
|December 14, 1999
PubMed
まとめ

メチレンテトラヒドロフラート還元酵素 (MTHFR) 677C-->T変異のホモジゴシティは,早期発症冠動脈疾患 (CAD) のリスクが高いことと関連しています. 低血葉酸レベルは,この遺伝子変異と早発性CADを有する個体でも観察されました.

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