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Updated: Jul 16, 2026

Generation of Human CD40-activated B cells
13:27

Generation of Human CD40-activated B cells

Published on: October 16, 2009

ベータ・アミロイド刺激後のCD40-CD40L相互作用によるマイクログリアル活性化

J Tan1, T Town, D Paris

  • 1The Roskamp Institute, University of South Florida, 3515 East Fletcher Avenue, Tampa, FL 33613, USA.

Science (New York, N.Y.)
|December 22, 1999
PubMed
まとめ

アルツハイマー病には炎症があり,ミクログリアが重要な役割を果たします. マイクログリアにおけるCD40-CD40L相互作用をターゲットにすることで,アルツハイマー病におけるアミロイドベータ誘発活性化とタウ病理を減らすことができる.

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Murine Model of CD40-activation of B cells

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Detection of CD40 Protein-Umbelliferone Interaction via Differential Scanning Fluorescence

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