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Updated: Jul 5, 2026

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
09:35

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform

Published on: July 16, 2016

ミトコンドリアグルタミン酸は,グルコース誘発インスリンエキソサイトーシスのメッセンジャーとして作用する

P Maechler1, C B Wollheim

  • 1Department of Internal Medicine, University Medical Centre, Geneva, Switzerland. pierre.maechler@medecine.unige.ch

Nature
|December 22, 1999
PubMed
まとめ

グルコースは,新しい経路を通じてインスリン分泌を刺激します. 臓のβ細胞は,ミトコンドリアで生成されるグルタミン酸を,カルシウムレベルに関係なく,グルコース代謝とインスリン放出を結びつける重要なメッセンジャーとして使用します.

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Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets09:41

Confocal Imaging of Neuropeptide Y-pHluorin: A Technique to Visualize Insulin Granule Exocytosis in Intact Murine and Human Islets

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