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Updated: Jul 14, 2026

Interview: Protein Folding and Studies of Neurodegenerative Diseases
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伝染性および遺伝的プリオン病は,神経変性病変の共通の経路を共有しています

R S Hegde1, P Tremblay, D Groth

  • 1Department of Physiology, University of California, San Francisco 94143, USA.

Nature
|January 5, 2000
PubMed
まとめ

感染性および遺伝性のプリオン病は,共通の神経変性経路を共有している可能性があります. この研究は,プリオンタンパク質 (PrP) Scの蓄積がPrP (CtmPrP) のトランスメブラン形態に影響することを明らかにし,プリオン疾患の病原性における統一されたメカニズムを示唆しています.

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