関連する実験動画

Updated: May 6, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

25.3K

B7RP-1とICOSによるT細胞共刺激

S K Yoshinaga1, J S Whoriskey, S D Khare

  • 1Amgen Inc., Thousand Oaks, California 91320, USA. syoshina@amgen.com

Nature
|January 5, 2000
PubMed
まとめ

新しい共刺激性受容体ICOSとそのリガンドであるB7関連タンパク質-1 (B7RP-1) が特定されました. この独特な経路は,CD28-B7相互作用とは独立してT細胞活性化と適応免疫を調節する.

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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay19:05

Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay

Published on: October 30, 2015

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Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production08:22

Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production

Published on: May 31, 2020

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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