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Updated: Jun 8, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
11:33

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes

Published on: March 12, 2013

ブルガダ症候群における心臓のNa(+) 経路機能不全は,β(1) -サブユニットによって悪化する

N Makita1, N Shirai, D W Wang

  • 1Department of Cardiovascular Medicine, Hokkaido University School of Medicine, Sapporo, Japan. makitan@med.hokudai.ac.jp

Circulation
|January 5, 2000
PubMed
まとめ

静脈細動に関連したヒトの心臓ナトリウムチャネル (hH1) 変異T1620Mは,β−1) サブユニットと共発現すると,ゲーティングが変化します. この相互作用は,より深刻な機能的欠陥を明らかにし,不律性メカニズムに寄与する可能性があります.

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A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines06:59

A Fluorescence-Based Assay of Membrane Potential for High-Throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines

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Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
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