関連する実験動画

Updated: Jul 20, 2026

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice
11:13

Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice

Published on: November 29, 2013

コリン投与:ネズミの脳のドーパミナージックニューロンにおけるチロシンヒドロキシラーゼの活性化

I H Ulus, R J Wurtman

    Science (New York, N.Y.)
    |December 3, 1976
    PubMed
    まとめ

    コリン投与は脳アセチルコリンレベルを上昇させ,ネズミのチロシンヒドロキシラーゼ活性を増大させます. アトロピンによって阻害されるこの効果は,コレンが神経伝達物質の放出に影響を及ぼすことを示唆しています.

    さらに関連する動画

    Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior10:05

    Rodent Brain Microinjection to Study Molecular Substrates of Motivated Behavior

    Published on: September 16, 2015

    An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation12:26

    An Invasive Method for the Activation of the Mouse Dentate Gyrus by High-frequency Stimulation

    Published on: June 2, 2018

    関連する概念動画

    Long-term Potentiation01:35

    Long-term Potentiation

    Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
    Long-term Potentiation01:25

    Long-term Potentiation

    Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
    Hebbian LTP
    LTP can occur when presynaptic neurons...
    Ligand-gated Ion Channels01:19

    Ligand-gated Ion Channels

    Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
    Three Subfamilies of Ligand-gated Ion Channels
    Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that include the...
    Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

    Ligand-Gated Ion Channel Receptor: Gating Mechanism

    Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...