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Updated: Jul 15, 2026

Clinical Application of Sleeping Beauty and Artificial Antigen Presenting Cells to Genetically Modify T Cells from Peripheral and Umbilical Cord Blood
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受精のための卵のプラズマ膜上のCD9の必要性

K Miyado1, G Yamada, S Yamada

  • 1Institute of Life Science, Kurume University, Kurume, Fukuoka 839-0861, Japan.

Science (New York, N.Y.)
|January 15, 2000
PubMed
まとめ

CD9タンパク質が欠けていたマウスは,精子と卵の融合が失敗したため不妊症を示した. これは,補助微受精が胚の発達を回復したため,CD9が受精に不可欠であることを示しています.

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During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...