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Updated: May 3, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
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酸化された低密度リポタンパク質は,基本的な線維芽細胞成長因子の発現を抑制することによって,内皮細胞の増殖を抑制します

C H Chen1, W Jiang, D P Via

  • 1Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. cchen@bcm.tmc.edu

Circulation
|January 19, 2000
PubMed
まとめ

酸化されたLDL (ox-LDL) は,基礎線維芽細胞成長因子 (bFGF) の発現を抑制することによって,内皮細胞の増殖を抑制します. この抑制は,オックス-LDLが内皮細胞に及ぼす細胞毒性作用に寄与し,動脈硬化症の新たな治療標的を示唆する.

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