臨床的に局所的な前立腺がんのための急性前立腺切除後の尿路と性機能:前立腺がんアウトカム研究
J L Stanford1, Z Feng, A S Hamilton
1Fred Hutchinson Cancer Research Center, Department of Epidemiology, University of Washington, Seattle 98109-1024, USA. jstanfor@fhcrc.org
JAMA
|January 27, 2000
まとめ
前立腺がんのための急性前立腺切除は,ほぼ60%の男性が不妊症を経験し,40%以上が性的パフォーマンス問題を報告していることで,性的機能に大きく影響します. 尿路機能も低下し,治療の合併症に関する患者と医師の情報に基づいた議論の必要性を強調しています.
科学分野:
- 泌尿器科 泌尿器科とは
- 腫瘍学 腫瘍学
- 公衆衛生は公衆衛生である.
背景:
- 人口ベースのコホートにおける前立腺切除による合併症に関するデータは限られている.
- 医師と患者は,治療の結果に関する包括的な情報が必要です.
研究 の 目的:
- 局所性前立腺がんの急性前立腺切除術後の泌尿器官および性機能の変化を評価する.
- 多様な患者集団における機能的アウトカムに関するデータを提供する.
主な方法:
- 人口ベースの縦断的なコホート研究 (前立腺がんアウトカム研究).
- 診断後最大24ヶ月間,1291人の男性を追跡調査した.
- 泌尿器系および性機能の評価は,基値および6,12および24ヶ月後に行われます.
主要な成果:
- 手術後の18ヶ月以上で,8.4%が incontinence,59.9%が impotence を経験しました.
- インポテンスの割合は,神経を節約する技術によって異なる (56.0%-65.6%).
- 性機能は年齢や人種によって大きく変化し,尿機能は年齢によって変化した.
結論:
- 根本的な前立腺切除は,実質的な勃起不全と尿路機能の低下と関連しています.
- 発見は,前立腺がんの治療選択肢をナビゲートする医師と患者にとって重要な洞察を提供します.
- 年齢と人種は,前立腺切除術後の性および尿路機能に影響を与える重要な要因です.
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