核酸アプタマーによる適応認識

T Hermann1, D J Patel

  • 1Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. thermann@sbnmr1.ski.mskcc.org

Science (New York, N.Y.)
|February 5, 2000
PubMed
まとめ

核酸アプタマーは,特定の分子に高親密度で結合するために選択されます. 構造研究は,スタッキング,水素結合,形状の互換性などの重要な相互作用を明らかにし,細胞認識イベントを反映しています.

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