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Updated: Jul 21, 2026

Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient
08:06

Preparation of Synaptic Plasma Membrane and Postsynaptic Density Proteins Using a Discontinuous Sucrose Gradient

Published on: September 3, 2014

神経伝達物質の分泌の欠如で脳のシナプスアセンブリ

M Verhage1, A S Maia, J J Plomp

  • 1Molecular Neuroscience, Rudolf Magnus Institute, University of Utrecht Medical Centre, Utrecht, Netherlands.

Science (New York, N.Y.)
|February 5, 2000
PubMed
まとめ

Munc18-1タンパク質が欠けているマウスは,神経伝達物質を分泌することができないが,それでも脳構造を形成する. これは,神経伝達物質の分泌は初期脳組成に不可欠ではないことを示唆しますが,シナプス結合の維持と神経変異の予防に不可欠です.

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