タンパク質とタンパク質の直接結合により,ドーパミンD5とガンマ-アミノバター酸A受容体間のクロストークが可能になる

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Updated: May 6, 2026

Genetic Incorporation of Biosynthesized L-dihydroxyphenylalanine DOPA and Its Application to Protein Conjugation
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Genetic Incorporation of Biosynthesized L-dihydroxyphenylalanine DOPA and Its Application to Protein Conjugation

Published on: August 24, 2018

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F Liu1, Q Wan, Z B Pristupa

  • 1Department of Psychiatry, University of Toronto, Ontario, Canada.

Nature
|February 5, 2000
PubMed
まとめ

ガンマアミノバター酸A (GABA) とドーパミンD5受容体は物理的に相互作用し,新しいシグナル伝達複合体を形成します. この相互作用により,相互に阻害的な機能効果が生じ,シナプス強さと精神運動機能に影響を与えます.

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