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Updated: Apr 14, 2026

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
07:17

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自己反応性CD8+T細胞のKIR発現は,T細胞の受容体エンゲージメントによって制御される

B Huard1, L Karlsson

  • 1The R.W. Johnson Pharmaceutical Research Institute, San Diego, California 92121, USA. huard@cmu.unige.ch

Nature
|February 5, 2000
PubMed
まとめ

T細胞のキラー阻害受容体 (KIR) は,T細胞受容体 (TCR) の関与なしにダウンレギュレーションされます. TCRの関与はKIR発現を維持し,T細胞の自己抗原に対する耐性におけるKIRのダイナミックな調節を示唆する.

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Generation of Human Chimeric Antigen Receptor Regulatory T Cells10:29

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