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Updated: May 2, 2026

Prediction and Validation of Gene Regulatory Elements Activated During Retinoic Acid Induced Embryonic Stem Cell Differentiation
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翼状ヘリックスタンパク質 hRFX1 の構造は,DNA結合の新しい方法を明らかにしています

K S Gajiwala1, H Chen, F Cornille

  • 1Laboratories of Molecular Biophysics, Pels Family Center for Biochemistry and Structural Biology, The Rockefeller University, New York, New York 10021, USA.

Nature
|March 8, 2000
PubMed
まとめ

調節因子X (RFX) タンパク質は,ユニークなベータ-ヘアピン構造を用いてDNAを結合する. この研究は,ヒトのRFX1DNA結合ドメインの1.5 Å解像度構造を明らかにし,遺伝子調節と疾患メカニズムに関する洞察を提供します.

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