心房細動に対するアブレーションとペースセラピー後の臨床結果:メタ解析

M A Wood¹, C Brown-Mahoney, G N Kay

¹Virginia Commonwealth University/Medical College of Virginia, Richmond, VA 23298-0053, USA.

Circulation

|March 15, 2000

まとめ

ラジオ周波数アブレーションとペースは,心房細動患者の生活の質を大幅に改善し,ヘルスケアの必要性を減少させます. この治療法では,1年間の死亡率が低く,医療による管理に匹敵する.

科学分野:

心臓病学心臓病学
電気生理学電気生理学
医療介入医療介入について

背景:

動脈動の管理には,しばしば心房動節の放射性アブレーションと,耐火性の症例の恒久的なペースングが含まれます.
これらの介入は,持続的な心房タキアリズム症候群の患者に症状の緩和を提供することを目的としています.

研究の目的:

アブレーションとペースセラピー後の臨床結果と生存率を明確にするために.
出版された文献からのデータをメタアナリシスで合成する.

主な方法:

21件の研究のデータを用いてメタアナリシスが行われました.
含有基準は,医学的に耐性のある心房タキアリズム,主に心房細動の患者1181人を含む.

主要な成果:

生活の質,心室機能,ヘルスケアの利用など,19の臨床結果指標において,有意な改善が観察されました.
射出分子は有意に改善した (P<0.001),一方,断片的縮小は改善の傾向を示した (P=0.08).
1年間の死亡率は,全死亡の6.3%,急性心臓死の2.0%でした.

結論:

アブレーションとペースセラピーは,医学的に耐性のある心房細動の患者に幅広い臨床的利点を提供します.
この治療法と関連した1年間の死亡率は低く,従来の医療療法と比較できます.

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