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Updated: May 12, 2026

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
10:24

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins

Published on: September 28, 2012

hCds1媒介によるBRCA1のリン酸化は,DNA損傷反応を調節する

J S Lee1, K M Collins, A L Brown

  • 1Laboratory of Molecular Hematology, NHLBI, NIH, Bethesda, Maryland 20892, USA.

Nature
|March 21, 2000
PubMed
まとめ

人間のCds1キナーゼ (hCds1/Chk2) は,DNA損傷後のBRCA1機能を調節する. hCds1によるBRCA1のリン酸化は,BRCA1変異細胞におけるDNA修復と細胞生存に不可欠である.

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