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抗原受容体シグナリングの持続時間は,CD4+対CD8+T細胞系統の運命を決定する

K Yasutomo1, C Doyle, L Miele

  • 1Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|April 13, 2000
PubMed
まとめ

同受容体によって影響されるT細胞受容体シグナル伝達の持続期間は,シモサイトがCD4+ヘルパー細胞かCD8+細胞毒性T細胞になるかを決定する. Notch-1はCD8+T細胞の成熟に不可欠であり,最初の系統選択ではありません.

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