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Updated: Jun 30, 2026

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts
10:55

Study of the DNA Damage Checkpoint using Xenopus Egg Extracts

Published on: November 5, 2012

ATMは,S段階のチェックポイント経路におけるp95/nbs1のリン酸化物

D S Lim1, S T Kim, B Xu

  • 1Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|April 15, 2000
PubMed
まとめ

アタキシア・テランジエクタシア (AT) とニーメーゲン破裂症候群 (NBS) は,放射線に対する感受性を共有しています. NBS細胞におけるATMキナーゼ活性化とATMに依存するp95/nbs1リン酸化は,これらのタンパク質を共通のDNA損傷反応経路で結びつける.

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