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認知症の発生に対するソーシャルネットワークの影響:コミュニティベースの縦断研究
L Fratiglioni1, H X Wang, K Ericsson
1Stockholm Gerontology Research Centre, and Division of Geriatric Medicine, NEUROTEC, Karolinska Institutet, Stockholm, Sweden. laura.fratiglioni@neurotec.ki.se
Lancet (London, England)
|April 25, 2000
まとめ
強力なソーシャルネットワークを維持することは,認知症から身を守るかもしれません. 限られた社会的つながりは,認知症のリスクを高め,認知の健康にとって社会的絆の重要性を強調しています.
科学分野:
- 神経科学は神経科学である.
- ゲロントロジーはゲロントロジーの学科です.
- 公衆衛生は公衆衛生である.
背景:
- 認知症の発症に社会的絆が及ぼす影響に関するデータは限られている.
- 社会的なつながりは,高齢者の認知健康にとって極めて重要です.
研究 の 目的:
- 認知症の発生率に対するソーシャルネットワークの構成要素の影響を調査する.
- 社会的つながりの異なる程度が認知症リスクにどのように影響するかを探求する.
主な方法:
- ストックホルムの非認知症の高齢者1203人のコミュニティベースのコホートを3年間追跡しました.
- 認知症の診断はDSM-IVの基準に従ったもので,ソーシャルネットワークのデータはインタビューによって収集された.
- コバリエータには,年齢,性別,教育,認知/機能的状態,うつ症状,血管疾患が含まれていました.
主要な成果:
- 孤独な生活や密接な社会的なつながりの欠如は,認知症のリスクを1.5倍増加させました.
- 独身や一人暮らしの人は,結婚した人と比較して1.9倍もリスクが高いという.
- 総合的なソーシャル・ネットワーク・インデックスでは,弱小または限られたネットワークを持つ場合,認知症のリスクが60%増加することが示され,社会的つながりの度合い (p=0.0009) に関して有意なグラデーションが観察されました.
結論:
- 広範囲にわたるソーシャルネットワークは,認知症から身を守るようである.
- これらの発見を確認し,潜在的な予防戦略の基礎となるメカニズムを明らかにするために,さらなる研究が必要です.
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