関連する実験動画
Updated: May 12, 2026

10:53
Optogenetic Stimulation of the Auditory Nerve
Published on: October 8, 2014
聴覚経路に向けられた網膜の投影によって媒介される視覚的行動.
L von Melchner1, S L Pallas, M Sur
1Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge 02139, USA.
Nature
|April 29, 2000
まとめ
フェレットでは,視覚入力を聴覚皮質に転送することで,機能的な視覚領域が作られました. これは,外的なインプットが,新皮質領域の知覚の様式を著しく指示することを示しています.
科学分野:
- 神経科学は神経科学である.
- 発達神経科学とは
- センサリー処理 センサリー処理
背景:
- 皮質の発達には,機能領域を形作る内在的および外在的な要因が含まれます.
- 皮質領域のモダリティを決定する際の外部インプットの役割は議論されています.
研究 の 目的:
- リダイレクトされた視覚入力が聴覚皮質における視覚的知覚と行動を誘発できるかどうかを調査する.
- 外的なインプットが知覚の様式をどの程度指示するかを判断する.
主な方法:
- 新生児のフェレットは,聴覚性タラムスへの網膜の投影の外科的誘導を受けた.
- 聴覚皮質の反応と,再配線経路を通じて提示される視覚刺激に対する行動的反応を分析した.
主要な成果:
- 再接続されたフェレットには,視覚的に反応する細胞と,聴覚皮質の網膜学的なマップが示された.
- これらのフレットは,光刺激に対する視覚的行動反応を示し,それらを視覚的であり,聴覚的ではないと認識しました.
- 格子空間周波数の差別化は,鋭度が低下したものの,再配線経路を通じて可能であった.
結論:
- 外的なインプットは,新皮質領域の知覚の様式を指示する上で重要な役割を果たします.
- 機能的な視覚能力は,クロスモダルの投影を通して,視覚以外の皮質領域で確立することができます.
関連する概念動画
Hearing
When we hear a sound, our nervous system is detecting sound waves—pressure waves of mechanical energy traveling through a medium. The frequency of the wave is perceived as pitch, while the amplitude is perceived as loudness.
The Retina
The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Auditory Pathway
Auditory pathways constitute the complex neural circuits responsible for transmitting and interpreting auditory information from the peripheral auditory system to the brain. Sound waves are initially captured by the outer ear, funneled through the ear canal, and reach the tympanic membrane (eardrum). These vibrations are transmitted via the middle ear's ossicles to the inner ear's cochlea.
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
Visual System
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
Auditory Perception
The auditory system is essential for sound perception, utilizing various critical structures. When sound waves enter the outer ear, they travel through the ear canal and cause the eardrum to vibrate. These vibrations are then transmitted to the middle ear, where three tiny bones – the malleus, incus, and stapes – amplify the sound. This amplification is crucial, as it ensures that the sound vibrations are strong enough to be conveyed to the inner ear. These vibrations then reach the cochlea, a...

