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Updated: Jun 30, 2026

Targeted DNA Methylation Analysis by Next-generation Sequencing
08:38

Targeted DNA Methylation Analysis by Next-generation Sequencing

Published on: February 24, 2015

CpGメチル化は,DNMT1が欠けているヒトがん細胞で維持されます

I Rhee1, K W Jair, R W Yen

  • 1The Johns Hopkins Oncology Center, and Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.

Nature
|May 9, 2000
PubMed
まとめ

DNAメチルトランスフェラーゼ1 (DNMT1) は,ヒトがん細胞のゲノムメチル化にのみ責任があるわけではありません. 他の酵素はメチル化を維持し,DNMT1が地域特異性を有することを示す.

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