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Updated: Jul 21, 2026

Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro
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Dioscin Mediated IgA Nephropathy Alleviation by Inhibiting B Cell Activation In Vivo and Decreasing Galactose-Deficient IgA1 Production In Vitro

Published on: October 13, 2023

ガッシャー病の新型経口治療は,N-ブチルデオキシノジリミシン (OGT 918) で基板生物合成を低下させる

T Cox1, R Lachmann, C Hollak

  • 1Department of Medicine, University of Cambridge, Addenbrooke's Hospital, UK.

Lancet (London, England)
|May 9, 2000
PubMed
まとめ

経口用OGT 918は,グルコシルトランスフェラーゼの阻害剤であり,ゴッシャー病に対する新しい治療法を提供します. この研究では,OGT 918が臓器の容量を大幅に減らし,神経病的でないゴッシャー病の患者の臨床マーカーを改善することを示しています.

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