関連する実験動画

Updated: May 9, 2026

Derivation of Glial Restricted Precursors from E13 mice
08:56

Derivation of Glial Restricted Precursors from E13 mice

Published on: June 20, 2012

ヒポカンプスのオリゴデンドロサイト前駆細胞のグルタマタージックシナプス

D E Bergles1, J D Roberts, P Somogyi

  • 1Vollum Institute, Oregon Health Sciences University, Portland 97201, USA. berglesd@ohsu.edu

Nature
|May 23, 2000
PubMed
まとめ

膠質細胞,特にオリゴデンドロサイト前駆細胞 (OPCs) は,アルファ-アミノ-3-ヒドロキシ-5-メチルイソクサゾールプロピオニック酸 (AMPA) 受容体経由で興奮神経細胞から急速な信号を受信する. このシナプス経路は,OPCカルシウムレベルに影響を与え,新しいニューロン-グリア通信経路を強調します.

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関連する概念動画

Glial Cells01:04

Glial Cells

Overview
Long-term Potentiation01:35

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre- and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when presynaptic neurons...
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...